Hazards identification potential acute health effects. Methylene chloride, methylene chloride cas number 75092. Figure 5 shows a picture of the container from which tal. The niosh recommended exposure limit rel for methylene chloride has not been established. Although it is not miscible with water, it is polar, and miscible with many organic solvents. July, 2010 and is valid for 5 years from this date.
It is slightly soluble in water and miscible with most organic solvents. Section 2 hazards identification statement of hazardous nature this product is classified as. Contact with eyes may cause severe irritation, and p ossible eye burns. Material safety data sheet page 1 of 2 methylene chloride. Vaporphase methylene blue is degraded in the atmosphere by reaction with photochemically produced hydroxyl radicals with an estimated halflife of about 1. This material is considered hazardous by the osha hazard communication. When heated to decomposition, emits acrid fumes of hydrogen chloride and phosgene.
The effects of acute exposure to methylene chloride dichloromethane are due to its cns depressant properties, which have resulted in fatalities. Dichloromethane is also known as methylene chloride and dcm. Trace impurities in solvents commonly used for gas. If released to the atmosphere, methylene blue will exist as both vapor and particulate in the ambient atmosphere. Locating and estimating sources of methylene chloride. July 3, 2007 the dow chemical company page 4 of 7 epidemiological studies on more than 6,000 people exposed to methylene chloride in their workplace using over 35 years of observations showed no. Ntp lists methylene chloride as a potential carcinogen. Methylene chloride, also known as dichloromethane and methylene dichloride, is a clear, colorless liquid with a slightly sweet scent that is primarily used as an industrial solvent and also as a potent paint stripper and paint thinner. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. To achieve the best quality of methylene chloride, trace amounts of impurity must be detected and removed from this solvent. Safety data sheet methylene chloride tech version 1. Figure 5 shows a picture of the container from which talstrip ii was poured in this incident.
Hazardous in case of skin contact irritant, permeator. This product contains a chemical known to the state of california to cause cancer. Methylene chloride 75 09 2 100 toxicological data on ingredients. Excess methyl chloride then reacts with added chlorine to produce methylene chloride, chloroform, and carbon tetrachloride as coproducts.
Methylene chloride is a solvent found in paint and varnish strippers that are used to remove paint or varnish. Page 2 of 5 safety data sheet methylene chloride take off contaminated clothing and wash before reuse. Methylene chloride is a solvent found in paint and varnish strippers that are used to remove paint or varnish coatings from a variety of surfaces. Parsons department of chemistry, arizona state university, tempe, az 85281 u. Methylene chloride revision date 28nov2019 eye contact rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. It is a very volatile liquid that penetrates readily through standard nitrile laboratory gloves. Methylene chloride has produced lung and liver tumors in mice and mammary tumors in female rats in a two year inhalation study.
Methylene chloride please ensure that this msds is given to, and explained to people using this product. Under normal conditions it has no flash point and can be. Skin contact wash off immediately with plenty of water for at least 15 minutes. This colorless, volatile liquid with a moderately sweet aroma is widely used as a solvent. Hydrogen chloride, chlorine, phosgene, oxides of carbon sensitivity to mechanical impact. Oct 21, 2014 at room temperature, methylene chloride is a clear, colorless liquid with a pleasant odor. Methylene chloride uses, benefits, and chemical safety facts. Methylene chloride is an aggressive solvent, making it a good choice for paint removers as well as an effective carrier and extraction solvent. Methylene chloride is removed from the body mainly in expired air and urine. Methylene chloridedichloromethane exposure can cause central nervous system, liver, and cardiovascular effects.
The recovery of methylene chloride from samples used in 17day storage tests remained above 99. Do not store together with reducing agents, heavymetal compounds, acids and alkalis. Metabolic conversion of methylene chloride to carbon monoxide may place persons with preexisting coronary artery disease at increased risk. A unit of srm 3008 consists of two 5 ml sealed borosilicate glass ampoules of a gravimetrically prepared solution of methylene chloride in methanol. Osha method 80 is an example of a validated method of sampling and analysis of mc. Dichloromethane material safety data sheet cas no 75092. Very hazardous in case of eye contact irritant, of ingestion, of inhalation. Refer to the niosh pocket guide to chemical hazards for more information. Mec prime mec prime is special high purity grade of methylene chloride for use in pharmaceutical drug tablet and film coating, antibiotics, vitamins, pharma carbomers mec prime worlds sole owner of mecprime, perkloneand triklone banner chemicals uk flying the flag of excellence for over 160 years queens award winner. In four human subjects exposed to methylene chloride 350 mgcu m for 2 hr, an average of 22.
A common synonym for methylene chloride is dichloromethane. Move the affected person from the hazardous exposure immediately. Employees in the area should be prepared to clean up minor spills, including most spills confined to the chemical fume hood. Anhydrous methyl chloride water content less than a dew point of 40of 40oc can be handled in carbon or stainless steel, c opper and bronze. Product identification name methylene chloride synonyms dichloromethane. Mdhs70 general methods for sampling airborne gases and vapours. Iarc lists methylene chloride in group 2b sufficient evidence in animals, insufficient evidence in humans. Methylene chloride is produced using methyl chloride and chlorine. Any additive, if used, in the product or process is of. Component immediately dangerous to life health idlh methylene chloride dichloromethane 75092 2300 ppm idlh propylene oxide 75569 400 ppm idlh hazardous combustion products. Reaction of hydrogen chloride and methanol result in methyl chloride. Hazardous to health regulations coshh 2002 as amended. Methylene chloride also known as dichloromethane is a volatile, colorless liquid with a sweet, chloroformlike odor. Most spills of methylene chloride dichloromethane outside of a chemical fume hood should be referred to the oeso spill response team by calling 911 from a campus phone or 9196842444 from any phone.
It is metabolized by the body to carbon monoxide, and can affect the bloods ability to transport oxygen. When handling dichloromethane in the workplace, use the following safety precautions. At low temperature and high pressure, the reaction is more selective to methylene chloride. In seven subjects exposed to 710 mgcu m for 2 hr, the corresponding value was 81. Detection of trace constituents in a solvent can be performed by concentrating a. Dichloromethane contains 40150 ppm amylene as stabilizer, acs reagent. Detecting trace amounts of impurity in methylene chloride. It is a solvent and is used many applications including paint removers. Product stewardship summary methylene chloride summary methylene chloride is a colorless, volatile liquid. Preliminary information on manufacturing, processing. Synonyms include dichloromethane, methylene bichloride, methane dichloride, and methylenedichloride. Methylene chloride ch2cl2 analytical methylene chloride. A dense, nonflammible colourless liquid at room temperature b.
Sep 26, 2019 toxicological profile for methylene chloride. Environmental protection agency epa issued a final rule banning the use of methylene chloride in all paint removers for consumer use, effective november 24, 2019. If unconscious place in recovery position and seek medical advice. Dichloromethane dcm or methylene chloride is an organochloride compound with the formula c h 2 cl 2. July 3, 2007 the dow chemical company page 4 of 7 epidemiological studies on more than 6,000 people exposed to methylene chloride in their workplace using over 35 years of observations showed no increase in deaths from cancer or any other disease. First aid measures remove victim to fresh air and keep at rest in a position comfortable for breathing. Safety data sheet methylene chloride page 5 issued. Methylene chloride is metabolically converted to carbon monoxide after systemic absorption, which yields increased concentrations of carboxyhemoglobin in the blood.
The recovery of analyte from the collection medium during storage must be 75% or greater. Methylene chloride is widely used as an extraction solvent in pharmaceutical, environmental, food and chemical industries. Oshas methylene chloride standard industries covered the osha methylene chloride standard title 29 code of federal regulations, parts 1910. Recommendations apply only to national institute for occupational safety and health niosh approved respirators. Material safety data sheet msds methylene chloride.
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